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Paulusworm
The Corn Snake Moderator
United Kingdom
686 Posts |
 Posted - 10/12/2008 : 22:09:49
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Have just read this in one of the journal articles though:
"The route of transmission is unknown, and the
snake mite, Ophionyssus natricis, is considered a vector
because many epizootics of inclusion body disease
have occurred in collections infested by this
parasite. At present, no serologic diagnostic test is available
to confirm the presence of this disease. Diagnosis is
generally made ante-mortem from the histologic review
of biopsies from the esophageal tonsils, stomach, or liver. Eosinophilic intracytoplasmic inclusions
are a hallmark of this disease. There is no
effective treatment, and snakes diagnosed with this
infection should be euthanatized."
I will keep digging around and if I find anything else I'll post it up  . |
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Edited by - Paulusworm on 10/12/2008 22:13:54 |
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Paulusworm
The Corn Snake Moderator
United Kingdom
686 Posts |
Posted - 10/12/2008 : 22:26:15
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This is a bit of a large post but lots of info:
7.3. Inclusion body disease
IBD is a highly prevalent disease in boid snakes. The name stems from the typical histopathological lesions with marked eosinophilic intracytoplasmic inclusions in the tissues. It sporadically occurs in colubrid and viperine snakes but it is not clear whether ‘‘IBD’’ in non-boid snakes has the same aetiology (Raymond et al., 2001; Fleming et al.,2003). Boid species that appear to be most sensitive to IBD are B. constrictor and tree boas (Corallus spp.), whereas pythons appear to be much less often affected than boas (Garner and Raymond, 2004). IBD is thought to be associated with retrovirus infection but little is known concerning the pathogenesis of the disease. Blood sucking parasites (e.g. snake mites O. natricis) are
candidates for the spread of the disease in any collection of snakes (Schumacher et al., 1994). Symptoms include mainly regurgitation, followed by inappetance and progressive nervous symptoms, eventually resulting in the death of the animal (Fig. 10). In some cases, dermatitis, vertebral anomalies and/or neoplastic processes are noted
(for a review see Vancraeynest et al., 2006). The disease is always fatal and can cause serious damage to collections.To limit the risk of introducing IBD into a snake collection, we recommend a combination of prolonged quarantine of 6 months, treatment against ectoparasites and the collection of liver biopsies for histological examination. Screening for the presence of IBD can be achieved by taking organ biopsies. A high number of hepatocytes in liver biopsies from affected snakes generally contain a large eosinophilic
intracytoplasmic inclusion, characteristic of the disease (Garner and Raymond, 2004). Alternatively, a biopsy from oesophageal tonsilar tissue can be used (Garner and Raymond,2004). Although the inclusions are often present in cells in the Jacobson’s organ, cytological examination of stained smears from this organ rarely reveals the presence of these inclusions. Blood smears can be used in boas providing a fast and non-invasive tool. Blood smears should be made twice during the quarantine period. Suspect smears can be confirmed using a liver biopsy. |
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Blackecho
The Corn Snake Admin
United Kingdom
4379 Posts |
Posted - 10/12/2008 : 22:27:06
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quote:
Originally posted by Paulusworm
Been doing a bit of digging around. It's caused by inclusion bodies
So Inclusions Bodies Disease is caused by inclusion bodies?
You students are a wonder  |
 
www.theroyalpython.co.uk/forum
Location: Rotherham
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Paulusworm
The Corn Snake Moderator
United Kingdom
686 Posts |
Posted - 10/12/2008 : 22:43:18
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Just read that first post back myself. It was a bitpoopwasn't it . In my defence I was a bit out of my face, due to the lovely painkillers that my doctor prescribed me, when I posted it. They'd worn off a bit by the time I posted the other two though.
If you need help with any of the big words in them B.E. don't be embaressed to ask |
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Blackecho
The Corn Snake Admin
United Kingdom
4379 Posts |
Posted - 11/12/2008 : 06:26:44
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Second post is very good Paul, although don't fancy blood smears and liver biopsies during quarantine  |
www.theroyalpython.co.uk/forum
Location: Rotherham
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Paulusworm
The Corn Snake Moderator
United Kingdom
686 Posts |
Posted - 11/12/2008 : 06:54:19
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I would love to believe that snake mites are the vectors but the first post was an extract from Schumacher's article and the second one is a different author quoting him on the issue of snake mites.
If he is correct and mites are the vector then the problem will be easily prevented in future. Unless I missed it when I read it there was no mention of airborne transmission at all and the research into it is ongoing.
Both articles were published in the last couple of years so stay positive people because they are trying to understand / cure / prevent it in future. |
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Edited by - Paulusworm on 11/12/2008 06:58:07 |
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Kazerella
The Corn Snake Admin
United Kingdom
3093 Posts |
Posted - 11/12/2008 : 13:18:29
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Good research Paulusworm.
Mites eh? You really are obsessed with creepy crawlies! From now on I will refer to you as 'bug man' in the same way that I now call Lewy 'Toad face' |
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gingerpony
Queen Bee
United Kingdom
10455 Posts |
Posted - 11/12/2008 : 13:54:45
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| yeah that's good stuff PW, got me thinking though - regurge as a one-off, where you can identify the cause isn't worth panicking over, but if it happens more than once then quarantine immediately? |
cornsnakes, ratsnakes, bullsnakes, boas and day geckos
Location:Leeds/York/Selby area |
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Paulusworm
The Corn Snake Moderator
United Kingdom
686 Posts |
Posted - 11/12/2008 : 14:22:09
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quote:
Originally posted by gingerpony
yeah that's good stuff PW, got me thinking though - regurge as a one-off, where you can identify the cause isn't worth panicking over, but if it happens more than once then quarantine immediately?
I would, just to be on the safe side.
GP: Do you have access to Vet. Journals at work? I can post the title of the article and which journal it was. If not I can add you to my msn messenger and send you the pdf files if you want. I have access through the Uni to sites like Science Direct, Wiley, etc. Let me know either way and I'll sort it for you. |
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Paulusworm
The Corn Snake Moderator
United Kingdom
686 Posts |
Posted - 11/12/2008 : 14:35:15
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quote:
Originally posted by Kazerella
Good research Paulusworm.
Mites eh? You really are obsessed with creepy crawlies! From now on I will refer to you as 'bug man' in the same way that I now call Lewy 'Toad face'
My son's got a t-shirt with that on the front. As soon as I can figure out how to work my scanner properly then I'll have one too. |
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gingerpony
Queen Bee
United Kingdom
10455 Posts |
Posted - 11/12/2008 : 14:50:22
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quote:
Originally posted by Paulusworm
GP: Do you have access to Vet. Journals at work? I can post the title of the article and which journal it was. If not I can add you to my msn messenger and send you the pdf files if you want. I have access through the Uni to sites like Science Direct, Wiley, etc. Let me know either way and I'll sort it for you.
that would be great thanks PW, we only get stuff relating to 'smallies' (small furry/fluffy animals) at the practice i work at now.
to make myself appear busy the other day i looked up all the reps we had on our computer system and read through the consultation notes. LMAO, we are NOT a reptile practice, fortunately at the initial phone call if somebody mentions the words 'snake' or 'reptile' we immediately give them details of a local specialist rep vet |
cornsnakes, ratsnakes, bullsnakes, boas and day geckos
Location:Leeds/York/Selby area |
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